منابع مشابه
Clinical and experimental skeletal muscle alcoholic myopathy.
Musculoskeletal symptoms are frequent in chronic alcohol abusers, but only relatively recently has a search been made for the pathological basis of these complaints. A prospective study of 150 unselected patients admitted with various forms of alcohol abuse, showed that on quadriceps muscle biopsy two-thirds of the patients had significant and specific atrophy of the type IIB (anaerobic, fast-t...
متن کاملCorticosteroid-induced myopathy and the respiratory muscles. Report of two cases.
Two women with connective tissue disease developed a characteristic steroid-induced myopathy. Reduced maximal transrespiratory pressures indicated reduced respiratory muscle strength. Gradual steroid dosage tapering resulted in prompt clinical improvement and marked increases in respiratory muscle strength, maximal inspiratory pressure increasing by 33 percent in one patient and by 70 percent i...
متن کاملAcute myopathy associated with large parenteral dose of corticosteroid in myasthenia gravis.
A 13 year old Greek girl with myasthenia gravis developed widespread muscle paralysis and atrophy after large parenteral doses of corticosteroids (5.48 g methylprednisolone). An electromyogram showed myopathy, creatine kinase concentration below normal, and a muscle biopsy showed severe myopathy with selective loss of the thick filaments (myosin). Previous reports of myopathy associated with la...
متن کاملImpaired Insulin/IGF Signaling in Experimental Alcohol-Related Myopathy
Alcohol-related myopathy (Alc-M) is highly prevalent among heavy drinkers, although its pathogenesis is not well understood. We hypothesize that Alc-M is mediated by combined effects of insulin/IGF resistance and oxidative stress, similar to the effects of ethanol on liver and brain. We tested this hypothesis using an established model in which adult rats were pair-fed for 8 weeks with isocalor...
متن کاملCorticosteroid therapy of experimental hydrocephalus after intraventricular-subarachnoid haemorrhage.
Symptomatic hydrocephalus after subarachnoid haemorrhage seems to result both from mechanical obstruction of arachnoid villi and basilar cisterns and from an inflammatory cellular reaction in the villi. Subarachnoid haemorrhage was induced in rabbits using whole blood injected through an implanted intraventricular needle. Control rabbits receiving intraventricular methyl prednisolone acetate bu...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1969
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780120505